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FKBP1A 抗体 (AA 1-108)

This anti-FKBP1A antibody is a 兔 多克隆 antibody detecting FKBP1A in WB 和 IHC. Suitable for 人.
产品编号 ABIN3022504
发货至: 中国

Quick Overview for FKBP1A 抗体 (AA 1-108) (ABIN3022504)

抗原

See all FKBP1A 抗体
FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

适用

  • 64
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  • 2
  • 1
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宿主

  • 64
  • 9

克隆类型

  • 55
  • 18
多克隆

标记

  • 35
  • 10
  • 9
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  • 2
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This FKBP1A antibody is un-conjugated

应用范围

  • 43
  • 29
  • 19
  • 16
  • 10
  • 8
  • 8
  • 5
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 11
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-108

    序列

    MGVQVETISP GDGRTFPKRG QTCVVHYTGM LEDGKKFDSS RDRNKPFKFM LGKQEVIRGW EEGVAQMSVG QRAKLTISPD YAYGATGHPG IIPPHATLVF DVELLKLE

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human FKBP12 (NP_463460.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

    别名

    FKBP1A

    背景

    The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.,FKBP1A,FKBP-12,FKBP-1A,FKBP1,FKBP12,PKC12,PKCI2,PPIASE,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,other,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Immunology & Inflammation,Regulator of mTOR complex function,Regulator,FKBP1A

    分子量

    11 kDa

    基因ID

    2280

    UniProt

    P62942

    途径

    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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