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GRK2 抗体 (AA 440-689)
This anti-GRK2 antibody is a 兔 多克隆 antibody detecting GRK2 in WB 和 IHC. Suitable for 人.
Quick Overview for GRK2 抗体 (AA 440-689) (ABIN3022346)
抗原
See all GRK2 (ADRBK1) 抗体
GRK2 (ADRBK1)
(Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
适用
All reactivities for GRK2 抗体
人
宿主
All hosts for GRK2 抗体
兔
克隆类型
All clonalities for GRK2 抗体
多克隆
标记
All conjugates for GRK2 抗体
This GRK2 antibody is un-conjugated
应用范围
All applications for GRK2 抗体
Western Blotting (WB), Immunohistochemistry (IHC)
GRK2抗体详情
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抗原表位
All epitopes for GRK2 抗体
AA 440-689
序列
LGRGAQEVKE SPFFRSLDWQ MVFLQKYPPP LIPPRGEVNA ADAFDIGSFD EEDTKGIKLL DSDQELYRNF PLTISERWQQ EVAETVFDTI NAETDRLEAR KKAKNKQLGH EEDYALGKDC IMHGYMSKMG NPFLTQWQRR YFYLFPNRLE WRGEGEAPQS LLTMEEIQSV EETQIKERKC LLLKIRGGKQ FILQCDSDPE LVQWKKELRD AYREAQQLVQ RVPKMKNKPR SPVVELSKVP LVQRGSANGL
交叉反应
人, 小鼠, 大鼠
产品特性
Polyclonal Antibodies
纯化方法
Affinity purification
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 440-689 of human GRK2 (NP_001610.2).
亚型
IgG
Alternatives
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使用细节
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应用备注
WB,1:500 - 1:2000,IHC,1:50 - 1:200
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid freeze / thaw cycles
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
GRK2目标详情
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抗原
GRK2 (ADRBK1)
(Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
别名
GRK2
背景
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.,GRK2,ADRBK1,BARK1,BETA-ARK1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,Immunology & Inflammation,Neuroscience,GRK2
分子量
79 kDa
基因ID
156
UniProt
P25098
途径
EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of G-Protein Coupled Receptor Protein Signaling , CXCR4-mediated Signaling Events , G-protein mediated Events , Interaction of EGFR with phospholipase C-gamma , Thromboxane A2 Receptor Signaling
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原发性抗体
anti-GRK2 抗体 (AA 440-689) (ABIN3022346)
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