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BDNF 抗体 (AA 20-247)

This anti-BDNF antibody is a 兔 多克隆 antibody detecting BDNF in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN3021893
发货至: 中国

Quick Overview for BDNF 抗体 (AA 20-247) (ABIN3021893)

抗原

See all BDNF 抗体
BDNF (Brain-Derived Neurotrophic Factor (BDNF))

适用

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宿主

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克隆类型

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多克隆

标记

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This BDNF antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 20-247

    序列

    PMKEANIRGQ GGLAYPGVRT HGTLESVNGP KAGSRGLTSL ADTFEHVIEE LLDEDQKVRP NEENNKDADL YTSRVMLSSQ VPLEPPLLFL LEEYKNYLDA ANMSMRVRRH SDPARRGELS VCDSISEWVT AADKKTAVDM SGGTVTVLEK VPVSKGQLKQ YFYETKCNPM GYTKEGCRGI DKRHWNSQCR TTQSYVRALT MDSKKRIGWR FIRIDTSCVC TLTIKRGR

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 20-247 of human BDNF (NP_733928.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Sidler, Aitken, Jiang, Sotiropoulos, Aggarwal, Anees, Chong, Siebenaller, Thanabalasingam, White, Choufani, Weksberg, Sangiorgi, Wrana, Delgado-Olguin, Bägli et al.: "DNA Methylation Reduces the Yes-Associated Protein 1/WW Domain Containing Transcription Regulator 1 Pathway and Prevents Pathologic Remodeling during Bladder Obstruction by Limiting Expression of ..." in: The American journal of pathology, Vol. 188, Issue 10, pp. 2177-2194, (2018) (PubMed).

    Hang, Zhao, Sun, Li, Han, Du, Li: "Brain-derived neurotrophic factor attenuates doxorubicin-induced cardiac dysfunction through activating Akt signalling in rats." in: Journal of cellular and molecular medicine, Vol. 21, Issue 4, pp. 685-696, (2017) (PubMed).

    Hang, Sun, Guo, Zhao, Du: "BDNF-mediates Down-regulation of MicroRNA-195 Inhibits Ischemic Cardiac Apoptosis in Rats." in: International journal of biological sciences, Vol. 12, Issue 8, pp. 979-89, (2017) (PubMed).

  • 抗原

    BDNF (Brain-Derived Neurotrophic Factor (BDNF))

    别名

    BDNF

    背景

    This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.,BDNF,ANON2,BULN2,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Obesity,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,BDNF

    分子量

    27 kDa/28 kDa/29 kDa/31 kDa/37 kDa

    基因ID

    627

    UniProt

    P23560

    途径

    RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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