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PYCARD 抗体 (AA 50-195)

This anti-PYCARD antibody is a 兔 多克隆 antibody detecting PYCARD in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN3021617
发货至: 中国

Quick Overview for PYCARD 抗体 (AA 50-195) (ABIN3021617)

抗原

See all PYCARD 抗体
PYCARD (PYD and CARD Domain Containing (PYCARD))

适用

  • 54
  • 10
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  • 1
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宿主

  • 46
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克隆类型

  • 44
  • 13
多克隆

标记

  • 35
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  • 2
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This PYCARD antibody is un-conjugated

应用范围

  • 39
  • 24
  • 17
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  • 1
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    • 1
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    AA 50-195

    序列

    LDLTDKLVSF YLETYGAELT ANVLRDMGLQ EMAGQLQAAT HQGSGAAPAG IQAPPQSAAK PGLHFIDQHR AALIARVTNV EWLLDALYGK VLTDEQYQAV RAEPTNPSKM RKLFSFTPAW NWTCKDLLLQ ALRESQSYLV EDLERS

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 50-195 of human ASC / TMS1 (NP_037390.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Deng, Zou, Xiong, Wang, Engelhardt, Ye, Yan, Qiu: "Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death by Inhibiting Apoptosis." in: Journal of virology, Vol. 91, Issue 24, (2017) (PubMed).

  • 抗原

    PYCARD (PYD and CARD Domain Containing (PYCARD))

    别名

    PYCARD

    背景

    This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.,PYCARD,ASC,CARD5,TMS,TMS-1,TMS1,PYD and CARD domain containing,ASC / TMS1,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Apoptosis,Caspases,PYCARD

    分子量

    15 kDa/19 kDa/21 kDa

    基因ID

    29108

    UniProt

    Q9ULZ3

    途径

    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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