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PPARG 抗体 (AA 50-150)

This anti-PPARG antibody is a 兔 多克隆 antibody detecting PPARG in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN3020844
发货至: 中国

Quick Overview for PPARG 抗体 (AA 50-150) (ABIN3020844)

抗原

See all PPARG 抗体
PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

适用

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宿主

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克隆类型

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多克隆

标记

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This PPARG antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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    AA 50-150

    序列

    LSVMEDHSHS FDIKPFTTVD FSSISTPHYE DIPFTRTDPV VADYKYDLKL QEYQSAIKVE PASPPYYSEK TQLYNKPHEE PSNSLMAIEC RVCGDKASGF H

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PPARgamma (NP_056953.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhang, Zhang, Xiao, Liu, Wang, Gao, Rong, Yao, Li, Xu: "The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway." in: Biochemical pharmacology, Vol. 101, pp. 100-11, (2016) (PubMed).

  • 抗原

    PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

    别名

    PPARG

    背景

    This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.,CIMT1,GLM1,NR1C3,PPARG1,PPARG2,PPARgamma,PPAR gamma,PPARG,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Signal Transduction,mTOR Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,Neurodegenerative Diseases,Stem Cells,Mesenchymal Stem Cells,PPARG

    分子量

    21 kDa/54 kDa/57 kDa

    基因ID

    5468

    UniProt

    P37231

    途径

    MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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