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- 抗原 See all GRP78 (HSPA5) 抗体
- GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
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抗原表位
- AA 550-650
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GRP78 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- EEDKKLKERI DTRNELESYA YSLKNQIGDK EKLGGKLSSE DKETMEKAVE EKIEWLESHQ DADIEDFKAK KKELEEIVQP IISKLYGSAG PPPTGEEDTA E
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide corresponding to a sequence within amino acids 550-650 of human BiP/GRP78 (NP_005338.1).
- 亚型
- IgG
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Kaempferol mitigates Endoplasmic Reticulum Stress Induced Cell Death by targeting caspase 3/7." in: Scientific reports, Vol. 8, Issue 1, pp. 2189, (2018) (PubMed).
: "Endoplasmic reticulum stress-dependent ROS production mediates synovial myofibroblastic differentiation in the immobilization-induced rat knee joint contracture model." in: Experimental cell research, Vol. 369, Issue 2, pp. 325-334, (2018) (PubMed).
: "Identification of ASB7 as ER stress responsive gene through a genome wide in silico screening for genes with ERSE." in: PLoS ONE, Vol. 13, Issue 4, pp. e0194310, (2018) (PubMed).
: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).
: "Crude Saponins of Panax notoginseng Have Neuroprotective Effects To Inhibit Palmitate-Triggered Endoplasmic Reticulum Stress-Associated Apoptosis and Loss of Postsynaptic Proteins in Staurosporine ..." in: Journal of agricultural and food chemistry, Vol. 64, Issue 7, pp. 1528-39, (2016) (PubMed).
: "
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Kaempferol mitigates Endoplasmic Reticulum Stress Induced Cell Death by targeting caspase 3/7." in: Scientific reports, Vol. 8, Issue 1, pp. 2189, (2018) (PubMed).
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- 抗原
- GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
- 别名
- HSPA5 (HSPA5 产品)
- 背景
- The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.,HSPA5,BIP,GRP78,HEL-S-89n,MIF2,Neuroscience,Neurodegenerative Diseases,HSPA5
- 分子量
- 72 kDa
- 基因ID
- 3309
- UniProt
- P11021
- 途径
- Thyroid Hormone Synthesis, ER-Nucleus Signaling
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