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FAS 抗体 (AA 150-250)

Name: FAS 抗体 (AA 150-250)
Brand: antibodies-online
SKU: ABIN3020739
Availability: OutOfStock

This anti-FAS antibody is a 兔多克隆 antibody detecting FAS in WB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.

Western blot analysis of extracts of various cell lines, using Fas antibody (ABIN3020738, ABIN3020739, ABIN3020740, ABIN1512896 and ABIN6213700) at 1:1000 dilution. (FAS 抗体 (AA 150-250))

Western blot analysis of extracts of SW480 cell lines, using FAS antibody. (FAS 抗体 (AA 150-250))

Immunohistochemistry (IHC) image for anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 150-250) antibody (ABIN3020739) (FAS 抗体 (AA 150-250))

IHC

Immunohistochemistry of paraffin-embedded human kidney using FAS antibody at dilution of 1:400 (200x lens). (FAS 抗体 (AA 150-250))

IHC

Immunohistochemistry of paraffin-embedded mouse kidney using FAS antibody at dilution of 1:400 (200x lens). (FAS 抗体 (AA 150-250))

IHC

5 images

(4 references)

产品编号 ABIN3020739

发货至: 中国

Quick Overview for FAS 抗体 (AA 150-250) (ABIN3020739)

抗原

See all FAS 抗体

FAS (TNF Receptor Superfamily, Member 6 (FAS))

适用

人

宿主

兔

克隆类型

多克隆

标记

This FAS antibody is un-conjugated

应用范围

Western Blotting (WB)

抗原表位
24

23

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16

8

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AA 150-250

序列

EHGIIKECTL TSNTKCKEEG SRSNLGWLCL LLLPIPLIVW VKRKEVQKTC RKHRKENQGS HESPTLNPET VAINLSDVDL SKYITTIAGV MTLSQVKGFV R

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

A synthetic peptide corresponding to a sequence within amino acids 150-250 of human Fas (NP_000034.1).

亚型

IgG
anti-TNF Receptor Superfamily, Member 6 (FAS) antibody
FAS 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 4F8H6 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 87-109), (N-Term) antibody
FAS 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-172) antibody
FAS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-169) antibody
FAS 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 21-170) antibody
FAS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibody
FAS 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2G3 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibody
FAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 5B4 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) antibody
FAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B6 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 26-96) antibody
FAS 适用: 人 FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal FAS-3112 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 185-211) antibody
FAS 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Wang, Yan, Xiao, Zhou, Liu, Zeng, Liu, Li, Yuan, Wu, Yi, Razack, Wen: "Anti-obesity effect of a traditional Chinese dietary habit-blending lard with vegetable oil while cooking." in: Scientific reports, Vol. 7, Issue 1, pp. 14689, (2017) (PubMed).

Chen, Gu, Jiang, Zhang: "Nuclear translocation of nuclear factor kappa B is regulated by G protein signaling pathway in arsenite-induced apoptosis in HBE cell line." in: Environmental toxicology, (2015) (PubMed).

Gu, Chen, Jiang, Zhang: "Resveratrol Synergistically Triggers Apoptotic Cell Death with Arsenic Trioxide via Oxidative Stress in Human Lung Adenocarcinoma A549 Cells." in: Biological trace element research, Vol. 163, Issue 1-2, pp. 112-23, (2015) (PubMed).

Chen, Jiang, Lai, Liu, Zhang: "Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression." in: Environmental and molecular mutagenesis, (2014) (PubMed).
抗原

FAS (TNF Receptor Superfamily, Member 6 (FAS))

别名

FAS

背景

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.,ALPS1A,APO-1,APT1,CD95,FAS1,FASTM,TNFRSF6,FAS,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,CD markers,Cytokines,TNF,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Neurodegenerative Diseases,FAS

分子量

9 kDa/11 kDa/14 kDa/16 kDa/24 kDa/35 kDa/37 kDa

基因ID

355

UniProt

P25445

途径

p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity