BMI1 抗体 (AA 120-326)
Our Local Distributor
北京 101111
Quick Overview for BMI1 抗体 (AA 120-326) (ABIN3020691)
抗原
See all BMI1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 120-326
-
序列
- EDKRIITDDE IISLSIEFFD QNRLDRKVNK DKEKSKEEVN DKRYLRCPAA MTVMHLRKFL RSKMDIPNTF QIDVMYEEEP LKDYYTLMDI AYIYTWRRNG PLPLKYRVRP TCKRMKISHQ RDGLTNAGEL ESDSGSDKAN SPAGGIPSTS SCLPSPSTPV QSPHPQFPHI SSTMNGTSNS PSGNHQSSFA NRPRKSSVNG SSATSSG
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 120-326 of human Bmi1 (NP_005171.4).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IP,1:50 - 1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid freeze / thaw cycles
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
-
别名
- BMI1
-
背景
- This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.,BMI1,FLVI2/BMI1,PCGF4,RNF51,flvi-2/bmi-1,Bmi1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,G1/S Checkpoint,BMI1
-
分子量
- 36 kDa
-
基因ID
- 648
-
UniProt
- P35226
-
途径
- Cell Division Cycle, Autophagy
抗原
-