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EGFR 抗体 (pTyr1068)

This anti-EGFR antibody is a 兔 多克隆 antibody detecting EGFR in WB 和 IP. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN3020070
发货至: 中国

Quick Overview for EGFR 抗体 (pTyr1068) (ABIN3020070)

抗原

See all EGFR 抗体
EGFR (Epidermal Growth Factor Receptor (EGFR))

适用

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宿主

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克隆类型

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多克隆

标记

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This EGFR antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
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    pTyr1068

    交叉反应

    人, 小鼠

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A phospho specific peptide corresponding to residues surrounding Y1068 of human EGFR

    亚型

    IgG
  • 应用备注

    WB,1:1000 - 1:2000,IP,1:50 - 1:100

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhang, Han, Lu, Zhao, Chen, Meng, Cao, Cai, Hu: "USP22 promotes resistance to EGFR-TKIs by preventing ubiquitination-mediated EGFR degradation in EGFR-mutant lung adenocarcinoma." in: Cancer letters, Vol. 433, pp. 186-198, (2018) (PubMed).

  • 抗原

    EGFR (Epidermal Growth Factor Receptor (EGFR))

    别名

    EGFR

    背景

    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.,EGFR,ERBB,ERBB1,HER1,NISBD2,PIG61,mENA,Cancer,Tumor biomarkers,Signal Transduction,G protein signaling,Kinase,Tyrosine kinases,Phospholipase Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,EGF,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Cardiovascular,Angiogenesis,Protein phosphorylation,EGFR

    分子量

    44 kDa/69 kDa/77 kDa/134 kDa

    基因ID

    1956

    UniProt

    P00533

    途径

    NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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