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c-MYC 抗体 (pSer373)

This anti-c-MYC antibody is a 兔 多克隆 antibody detecting c-MYC in WB. Suitable for 人.
产品编号 ABIN3019599
发货至: 中国

Quick Overview for c-MYC 抗体 (pSer373) (ABIN3019599)

抗原

See all c-MYC (MYC) 抗体
c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

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宿主

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克隆类型

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多克隆

标记

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This c-MYC antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pSer373

    交叉反应

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A phospho specific peptide corresponding to residues surrounding S373 of human c-Myc

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:1000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

    别名

    MYC

    背景

    The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.,MRTL,MYCC,bHLHe39,c-Myc,MYC,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor biomarkers,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell differentiation,G1/S Checkpoint,Hedgehog Signaling Pathway,Notch Signaling Pathway,Endocrine & Metabolism,Warburg Effect,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Stem Cells,Protein phosphorylation,MYC

    分子量

    48 kDa/50 kDa

    基因ID

    4609

    UniProt

    P01106

    途径

    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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