POMC 抗体 (AA 1-267)
Quick Overview for POMC 抗体 (AA 1-267) (ABIN3017231)
抗原
See all POMC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-267
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序列
- MPRSCCSRSG ALLLALLLQA SMEVRGWCLE SSQCQDLTTE SNLLECIRAC KPDLSAETPM FPGNGDEQPL TENPRKYVMG HFRWDRFGRR NSSSSGSSGA GQKREDVSAG EDCGPLPEGG PEPRSDGAKP GPREGKRSYS MEHFRWGKPV GKKRRPVKVY PNGAEDESAE AFPLEFKREL TGQRLREGDG PDGPADDGAG AQADLEHSLL VAAEKKDEGP YRMEHFRWGS PPKDKRYGGF MTSEKSQTPL VTLFKNAIIK NAYKKGE
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-267 of human POMC (NP_000930.1).
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亚型
- IgG
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anti-Proopiomelanocortin (POMC) (C-Term) antibody
Verified POMC 适用: 人 ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (N-Term) antibodyPOMC 适用: 人, 小鼠, 大鼠 ELISA, IHC, FACS, IF, Coat, StM 宿主: 小鼠 Monoclonal 57 unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-150) antibodyPOMC 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 6D2B5 unconjugated
anti-Proopiomelanocortin (POMC) antibodyPOMC 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 205-267) antibodyPOMC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-150) antibodyPOMC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D3A10 unconjugated
anti-Proopiomelanocortin (POMC) (AA 138-176), (Middle Region) antibodyPOMC 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 27-235) antibodyPOMC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- POMC (Proopiomelanocortin (POMC))
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别名
- POMC
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背景
- This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. The antimicrobial melanotropin alpha peptide exhibits antibacterial and antifungal activity. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.,POMC,ACTH,CLIP,LPH,MSH,NPP,POC,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,POMC
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分子量
- 29 kDa
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基因ID
- 5443
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UniProt
- P01189
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途径
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
抗原
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