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CCR2 抗体 (AA 315-374)

This anti-CCR2 antibody is a 兔 多克隆 antibody detecting CCR2 in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN3016845
发货至: 中国

Quick Overview for CCR2 抗体 (AA 315-374) (ABIN3016845)

抗原

See all CCR2 抗体
CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

适用

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宿主

  • 90
  • 13
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克隆类型

  • 82
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  • 2
多克隆

标记

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This CCR2 antibody is un-conjugated

应用范围

  • 46
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Western Blotting (WB)
  • 抗原表位

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    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    • 1
    AA 315-374

    序列

    LFHIALGCRI APLQKPVCGG PGVRPGKNVK VTTQGLLDGR GKGKSIGRAP EASLQDKEGA

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 315-374 of human CCR2 (NP_001116513.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Deci, Ferguson, Scatigno, Nguyen: "Modulating Macrophage Polarization through CCR2 Inhibition and Multivalent Engagement." in: Molecular pharmaceutics, Vol. 15, Issue 7, pp. 2721-2731, (2018) (PubMed).

  • 抗原

    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

    别名

    CCR2

    背景

    This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.,CCR2,CC-CKR-2,CCR-2,CCR2A,CCR2B,CD192,CKR2,CKR2A,CKR2B,CMKBR2,MCP-1-R,FLJ78302,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,Cardiovascular,CCR2

    分子量

    41 kDa

    基因ID

    729230

    UniProt

    P41597

    途径

    cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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