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RUNX2 抗体 (AA 242-521)

Name: RUNX2 抗体 (AA 242-521)
Brand: antibodies-online
SKU: ABIN3016834
Availability: OutOfStock

This anti-RUNX2 antibody is a 兔多克隆 antibody detecting RUNX2 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 5+ publications.

Western blot analysis of extracts of OS-RC-2 cell lines, using RUNX2 antibody. (RUNX2 抗体 (AA 242-521))

Immunohistochemistry of paraffin-embedded mouse salivary gland using RUNX2 Rabbit pAb (ABIN3016833, ABIN3016834, ABIN3016835 and ABIN6219851) at dilution of 1:100 (40x lens). (RUNX2 抗体 (AA 242-521))

IHC

Western blot analysis of extracts of various cell lines, using RUNX2 antibody. (RUNX2 抗体 (AA 242-521))

PKD1 contributed to osteoblastic development. (RUNX2 抗体 (AA 242-521))

PKD1 impaired osteoblast differentiation through JAK1/STAT3 and p38 signaling pathway. (RUNX2 抗体 (AA 242-521))

Effects of BW001 and FC001 on protein expression of the cyclin D1/Runx2 regulation network. (RUNX2 抗体 (AA 242-521))

Western blot analysis of extracts of Mouse testis, using RUNX2 antibody (ABIN3016833, ABIN3016834, ABIN3016835 and ABIN6219851) at 1:1000 dilution. (RUNX2 抗体 (AA 242-521))

Immunohistochemistry of paraffin-embedded rat spleen using RUNX2 Rabbit pAb (ABIN3016833, ABIN3016834, ABIN3016835 and ABIN6219851) at dilution of 1:300 (40x lens). (RUNX2 抗体 (AA 242-521))

IHC

Immunofluorescence analysis of rat spleen cells using RUNX2 Rabbit pAb (ABIN3016833, ABIN3016834, ABIN3016835 and ABIN6219851) at dilution of 1:100 (40x lens). (RUNX2 抗体 (AA 242-521))

12 images

(5 references)

产品编号 ABIN3016834

发货至: 中国

Quick Overview for RUNX2 抗体 (AA 242-521) (ABIN3016834)

抗原

See all RUNX2 抗体

RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This RUNX2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product RUNX2 Primary Antibody

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AA 242-521

序列

FSDRLSDLGR IPHPSMRVGV PPQNPRPSLN SAPSPFNPQG QSQITDPRQA QSSPPWSYDQ SYPSYLSQMT SPSIHSTTPL SSTRGTGLPA ITDVPRRISD DDTATSDFCL WPSTLSKKSQ AGASELGPFS DPRQFPSISS LTESRFSNPR MHYPATFTYT PPVTSGMSLG MSATTHYHTY LPPPYPGSSQ SQSGPFQTSS TPYLYYGTSS GSYQFPMVPG GDRSPSRMLP PCTTTSNGST LLNPNLPNQN DGVDADGSHS SSPTVLNSSG RMDESVWRPY

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 242-521 of human RUNX2 (NP_001019801.3).

亚型

IgG
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibody
RUNX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibody
RUNX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F5 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (N-Term) antibody
RUNX2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 445-474) antibody
RUNX2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibody
RUNX2 适用: 人, 大鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 3F5 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibody
RUNX2 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (Internal Region) antibody
RUNX2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) antibody
RUNX2 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibody
RUNX2 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 1D2 unconjugated

anti-Runt-Related Transcription Factor 2 (RUNX2) (pSer451) antibody
RUNX2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:200 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:200

限制

仅限研究用
缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Zhang, Wang, Zeng, Yan, Ouyang, Liu, Sun, Zhao, Fang, Pan, Xie, Yang, Zhang, Bai, Cai: "mTORC1 activation downregulates FGFR3 and PTH/PTHrP receptor in articular chondrocytes to initiate osteoarthritis." in: Osteoarthritis and cartilage, Vol. 25, Issue 6, pp. 952-963, (2018) (PubMed).

Gao, Li, Li: "Exendin-4 promotes the osteogenic differentiation of osteoblasts via the Hedgehog/Gli1 signaling pathway." in: American journal of translational research, Vol. 10, Issue 1, pp. 315-324, (2018) (PubMed).

Wang, Zhang, Sun, Wang, Yang, Yang, Zhang, Luo, Wang, Jiang, Zeng, Cai, Bai: "Intra-articular Delivery of Antago-miR-483-5p Inhibits Osteoarthritis by Modulating Matrilin 3 and Tissue Inhibitor of Metalloproteinase 2." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 25, Issue 3, pp. 715-727, (2017) (PubMed).

Li, Xu, Xing, Qian, Chen, Gu, Guo, Lai, Zhao, Li, Wang, Wang, Deng: "A Conditional Knockout Mouse Model Reveals a Critical Role of PKD1 in Osteoblast Differentiation and Bone Development." in: Scientific reports, Vol. 7, pp. 40505, (2017) (PubMed).

Wu, Wang, Ji, Ou, Xia, Zhang, Zhao: "C4orf7 modulates osteogenesis and adipogenesis of human periodontal ligament cells." in: American journal of translational research, Vol. 9, Issue 12, pp. 5708-5718, (2017) (PubMed).
抗原

RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

别名

RUNX2

背景

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.,RUNX2,AML3,CBF-alpha-1,CBFA1,CCD,CCD1,CLCD,OSF-2,OSF2,PEA2aA,PEBP2aA,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Extracellular Matrix,Bone,Hippo Signaling Pathway,Stem Cells,Mesenchymal Stem Cells,Target gene,RUNX2

分子量

54 kDa/55 kDa/56 kDa

基因ID

860

UniProt

Q13950