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Cullin 1 抗体 (AA 500-776)

This anti-Cullin 1 antibody is a 兔 多克隆 antibody detecting Cullin 1 in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN3015864
发货至: 中国

Quick Overview for Cullin 1 抗体 (AA 500-776) (ABIN3015864)

抗原

See all Cullin 1 (CUL1) 抗体
Cullin 1 (CUL1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cullin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 500-776

    序列

    YTSKLQRMFQ DIGVSKDLNE QFKKHLTNSE PLDLDFSIQV LSSGSWPFQQ SCTFALPSEL ERSYQRFTAF YASRHSGRKL TWLYQLSKGE LVTNCFKNRY TLQASTFQMA ILLQYNTEDA YTVQQLTDST QIKMDILAQV LQILLKSKLL VLEDENANVD EVELKPDTLI KLYLGYKNKK LRVNINVPMK TEQKQEQETT HKNIEEDRKL LIQAAIVRIM KMRKVLKHQQ LLGEVLTQLS SRFKPRVPVI KKCIDILIEK EYLERVDGEK DTYSYLA

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 500-776 of human Cullin 1 (NP_003583.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:10 - 1:100

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Chen, Xu, Yang, Zhang, Wu, Chen, Li, Wang, Li, Li, Dai: "Upregulation of miR-223 in the rat liver inhibits proliferation of hepatocytes under simulated microgravity." in: Experimental & molecular medicine, Vol. 49, Issue 6, pp. e348, (2018) (PubMed).

    Liao, Jiang, He, Ni, Tu, Zhang, Wang, Lou, Quan, Wang: "NEDD8-mediated neddylation is required for human endometrial stromal proliferation and decidualization." in: Human reproduction (Oxford, England), Vol. 30, Issue 7, pp. 1665-76, (2016) (PubMed).

  • 抗原

    Cullin 1 (CUL1)

    别名

    CUL1

    背景

    The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases. Humans express seven cullin proeins: CUL1-3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality.,Cullin 1,CUL1,cullin-1,MGC149834,MGC149835,Cancer,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,CUL1

    分子量

    89 kDa

    基因ID

    8454

    UniProt

    Q13616

    途径

    Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases, Regulation of Cell Size
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