Cullin 1 抗体 (AA 500-776)
Quick Overview for Cullin 1 抗体 (AA 500-776) (ABIN3015864)
抗原
See all Cullin 1 (CUL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 500-776
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序列
- YTSKLQRMFQ DIGVSKDLNE QFKKHLTNSE PLDLDFSIQV LSSGSWPFQQ SCTFALPSEL ERSYQRFTAF YASRHSGRKL TWLYQLSKGE LVTNCFKNRY TLQASTFQMA ILLQYNTEDA YTVQQLTDST QIKMDILAQV LQILLKSKLL VLEDENANVD EVELKPDTLI KLYLGYKNKK LRVNINVPMK TEQKQEQETT HKNIEEDRKL LIQAAIVRIM KMRKVLKHQQ LLGEVLTQLS SRFKPRVPVI KKCIDILIEK EYLERVDGEK DTYSYLA
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 500-776 of human Cullin 1 (NP_003583.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:10 - 1:100
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Upregulation of miR-223 in the rat liver inhibits proliferation of hepatocytes under simulated microgravity." in: Experimental & molecular medicine, Vol. 49, Issue 6, pp. e348, (2018) (PubMed).
: "NEDD8-mediated neddylation is required for human endometrial stromal proliferation and decidualization." in: Human reproduction (Oxford, England), Vol. 30, Issue 7, pp. 1665-76, (2016) (PubMed).
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: "Upregulation of miR-223 in the rat liver inhibits proliferation of hepatocytes under simulated microgravity." in: Experimental & molecular medicine, Vol. 49, Issue 6, pp. e348, (2018) (PubMed).
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- Cullin 1 (CUL1)
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别名
- CUL1
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背景
- The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases. Humans express seven cullin proeins: CUL1-3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality.,Cullin 1,CUL1,cullin-1,MGC149834,MGC149835,Cancer,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,CUL1
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分子量
- 89 kDa
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基因ID
- 8454
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UniProt
- Q13616
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途径
- Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases, Regulation of Cell Size
抗原
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