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CD44 抗体

This anti-CD44 antibody is a 小鼠 单克隆 antibody detecting CD44 in FACS, WB, IHC, IHC (p), IP 和 IHC (fro). Suitable for 人, Baboon 和 Green Monkey.
产品编号 ABIN298843
发货至: 中国

Quick Overview for CD44 抗体 (ABIN298843)

抗原

See all CD44 抗体
CD44

适用

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人, Baboon, Green Monkey

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD44 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

156-3C11
  • 特异性

    Recognizes human CD44, a 90kD type I transmembrane protein which is otherwise known as HCAM or CD44s. Various isoforms of CD44 exist. The 90kD standard form, recognized by this, is expressed on leucocytes, erythrocytes, white matter of the brain and some epithelial cells of the breast and small intestine. Antibodies produced by clone 156-3C11 recognize epitope 3, which is a protease resistant epitope on the CD44 Molecule. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.

    纯化方法

    Affinity purified

    免疫原

    Stimulated human leucocytes.

    亚型

    IgG2a
  • 应用备注

    Approved: Flo (1:50 - 1:100), IHC, IHC-Fr (1:100), IHC-P (1:100), IP, WB

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. Western Blot: LS-C58044 detects a band of approximately 80kD in HeLa cell lysates. Immunohistology: This product requires

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Short term: -20°C
    Long term: -20°C.
  • 抗原

    CD44

    别名

    CD44

    背景

    Name/Gene ID: CD44

    Synonyms: CD44, CDW44, CD44 antigen, Cell surface glycoprotein CD44, CSPG8, ECMR-III, Epican, HUTCH-I, LHR, MDU2, MC56, MIC4, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, PGP-I, Pgp1, Phagocytic glycoprotein I, MDU3, CD44R, HCELL, Heparan sulfate proteoglycan

    基因ID

    960

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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