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SIGLEC7 抗体

The 小鼠 单克隆 anti-SIGLEC7 antibody is suitable to detect SIGLEC7 in samples from 人. It has been validated for IHC, FACS 和 IHC (fro).
产品编号 ABIN298835
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SIGLEC7 抗体 (ABIN298835)

抗原

See all SIGLEC7 抗体
SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

适用

  • 84
  • 11
  • 6
  • 3
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  • 2
  • 1
  • 1

宿主

  • 60
  • 24
  • 2
小鼠

克隆类型

  • 58
  • 23
  • 3
单克隆

标记

  • 48
  • 9
  • 9
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIGLEC7 antibody is un-conjugated

应用范围

  • 59
  • 36
  • 36
  • 18
  • 13
  • 9
  • 8
  • 3
  • 2
  • 2
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  • 1
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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

5-386
  • 特异性

    Specific for human CDw328, a type I transmembrane glycoprotein and member of the Siglec (sialic acid binding Ig-like lectin) family, designated Siglec-7, originally identified as an inhibitory NK cell receptor (NKR) and negative regulator of NK activation, attributed to ITIM recruitment of SHP-1 phosphatase. CDw328 is expressed predominantly by natural killer cells (NK) and to a lesser extent by monocytes and granulocytes and, like Siglec-5 (CD170), has been shown to bind to sialylated ligands of targets through recognition of sialic acid in both the alpha-2,3- and alpha-2,6- glycosidic linkage.

    纯化方法

    Affinity purified

    免疫原

    Monocyte-derived dendritic cells.

    Type of Immunogen: Cells

    亚型

    IgG1
  • 应用备注

    Approved: Flo (1:100 - 1:200), IHC, IHC-Fr (1:100)

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原

    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

    别名

    SIGLEC7 / CD328

    背景

    Name/Gene ID: SIGLEC7
    Family: Immunoglobulin

    Synonyms: SIGLEC7, AIRM-1, AIRM1, CD328 antigen, CDw328, CD328, D-siglec, QA79, SIGLEC-7, QA79 membrane protein

    基因ID

    27036

    UniProt

    Q9Y286
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