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CD51 抗体

ITGAV 适用: 小鼠 IHC, FACS, IP, IHC (fro) 宿主: 大鼠 Monoclonal RMV-7 unconjugated
产品编号 ABIN298790
发货至: 中国
  • 抗原 See all CD51 (ITGAV) 抗体
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    适用
    • 94
    • 50
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    小鼠
    宿主
    • 64
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    大鼠
    克隆类型
    • 56
    • 46
    单克隆
    标记
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    This CD51 antibody is un-conjugated
    应用范围
    • 46
    • 46
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    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Recognizes murine CD51, a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the integrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 function as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
    纯化方法
    Affinity purified
    免疫原
    Cultured LAK cells from Balb/c mice.
    克隆位点
    RMV-7
    亚型
    IgG1
    Top Product
    Discover our top product ITGAV Primary Antibody
  • 应用备注
    Approved: Flo (1:25 - 1:100), IHC, IHC-Fr (1:25 - 1:100), IP

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.
    说明

    Target Species of Antibody: Mouse

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4, 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    别名
    ITGAV/Integrin Alpha V/CD51 (ITGAV 产品)
    背景
    Name/Gene ID: ITGAV
    Family: Integrin

    Synonyms: ITGAV, CD51, CD51 antigen, Integrin, alpha V, MSK8, Integrin Alpha V, Integrin alpha-V, VNRA, Vitronectin receptor, Integrin alphaVbeta3, VTNR
    基因ID
    3685
    UniProt
    P06756
    途径
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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