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NLRP3 抗体 (AA 82-93)

NLRP3 适用: 人, 猴 ELISA, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN297366
发货至: 中国
  • 抗原 See all NLRP3 抗体
    NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
    抗原表位
    • 16
    • 9
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    AA 82-93
    适用
    • 90
    • 56
    • 38
    • 23
    • 4
    • 2
    • 1
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    人, 猴
    宿主
    • 86
    • 11
    • 2
    • 1
    山羊
    克隆类型
    • 85
    • 15
    多克隆
    标记
    • 43
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    This NLRP3 antibody is un-conjugated
    应用范围
    • 62
    • 39
    • 22
    • 13
    • 13
    • 10
    • 10
    • 8
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    • 6
    • 3
    • 1
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    ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    品牌
    IHC-plus™
    特异性
    Human NLRP3. This antibody is expected to recognise all five reported isoforms (NP_004886.3, NP_899632.1, NP_001230062.1, NP_001120933.1, NP_001120934.1). Reported variants represent identical protein (NP_004886.3 and NP_001073289.1).
    预测反应
    Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Bat, Panda, Pig (92%) Dog, Bovine, Rabbit (83%).
    纯化方法
    Immunoaffinity purified
    免疫原
    Synthetic peptide C-DLYEKAKRDEPK from an internal region of human NLRP3 (NP_004886.3, NP_899632.1, NP_001230062.1, NP_001120933.1, NP_001120934.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Bat, Panda, Pig (92%), Dog, Bovine, Rabbit (83%).

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product NLRP3 Primary Antibody
  • 应用备注
    Approved: IHC, IHC-P (2.5 μg/mL), Peptide-ELISA (1:64000)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Minimize freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原
    NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
    别名
    NALP3 / NLRP3 (NLRP3 产品)
    别名
    CIAS1 antibody, Nalp3 antibody, avp antibody, cias1 antibody, nalp3 antibody, pypaf1 antibody, agtavprl antibody, AGTAVPRL antibody, AII antibody, AVP antibody, C1orf7 antibody, CLR1.1 antibody, FCAS antibody, FCU antibody, MWS antibody, NALP3 antibody, PYPAF1 antibody, AII/AVP antibody, Cias1 antibody, Mmig1 antibody, Pypaf1 antibody, NLR family pyrin domain containing-like antibody, NLR family pyrin domain containing 3 antibody, NLR family, pyrin domain containing 3 L homeolog antibody, NLR family, pyrin domain containing 3 antibody, NLRPL antibody, NLRP3 antibody, nlrp3.L antibody, Nlrp3 antibody
    背景
    Name/Gene ID: NLRP3

    Synonyms: NLRP3, AGTAVPRL, AII, C1orf7, Caterpiller protein 1.1, Cryopyrin, FCAS, FCU, PYPAF1, NALP3, CIAS1, CLR1.1, MWS
    基因ID
    114548
    NCBI登录号
    NP_004886, NP_899632, NP_001230062, NP_001120933, NP_001120934
    UniProt
    Q96P20
    途径
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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