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ICAM2 抗体 (PE)

This PE-conjugated 小鼠 单克隆 anti-ICAM2 antibody (Clone CBR-IC2-2) specifically detects ICAM2 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN2967163
发货至: 中国
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Quick Overview for ICAM2 抗体 (PE) (ABIN2967163)

抗原

See all ICAM2 抗体
ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ICAM2 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

CBR-IC2-2
  • 原理

    Anti-Hu CD102 PE

    特异性

    The mouse monoclonal antibody CBR-IC2/2 recognizes an extracellular epitope of CD102 (ICAM-2), an approximately 55 kDa type I transmembrane glycoprotein expressed mainly on vascular endothelial cells and folicular dendritic cells, in lower amount on lymphocytes, monocytes and platelets.

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    Human CD102 cDNA transfected COS cells

    亚型

    IgG2a
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

    别名

    CD102

    背景

    Intercellular adhesion molecule 2,CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration.,ICAM2

    基因ID

    3384

    UniProt

    P13598
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