Growth Hormone 1 抗体
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北京 101111
Quick Overview for Growth Hormone 1 抗体 (ABIN294957)
抗原
See all Growth Hormone 1 (GH1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human growth hormone (hGH), a 22kD polypeptide synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. It is also referred to as somatotropin. Many different isoforms exist in humans, from monomers to pentamers, disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. Human GH binds to two GH receptors and induces signal transduction through receptor dimerization. Growth hormone plays an important role in growth and cell production. An excess of GH results in acromegaly or gigantism, characterized by excessive growth. It can also be accompanied by muscle weakness, insulin resistance and pressure on nerves. Deficiency of GH may result in lack of strength, energy and bone mass. May be used to detect human growth hormone in ELISA assays.
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纯化方法
- Affinity purified
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免疫原
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Purified recombinant human growth hormone.
Type of Immunogen: Recombinant protein -
亚型
- IgG1
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应用备注
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Approved: ELISA
Usage: ELISA: This product may be used in an indirect ELISA -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Short term: -20°C
Long term: -20°C.
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- Growth Hormone 1 (GH1)
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别名
- GH / Growth Hormone
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背景
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Name/Gene ID: GH1
Family: Somatotropin
Synonyms: GH1, Growth hormone, GH, GHN, IGHD1B, GH-N, Pituitary growth hormone, Growth hormone 1, HGH-N, Somatotropin -
基因ID
- 2688
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UniProt
- P01241
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途径
- NF-kappaB Signaling, JAK/STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
抗原
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