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Beclin 1 抗体

This anti-Beclin 1 antibody is a 兔 多克隆 antibody detecting Beclin 1 in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN2868739
发货至: 中国

Quick Overview for Beclin 1 抗体 (ABIN2868739)

抗原

See all Beclin 1 (BECN1) 抗体
Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Beclin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 特异性

    Predicted molecular weight at ~51 kDa. Observed a secondary band on some lysates at ~30 kDa.

    交叉反应

    人, 大鼠

    纯化方法

    Peptide Affinity Purified

    免疫原

    Synthetic peptide from the mid-protein of human Beclin 1
  • 应用备注

    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.

    说明

    A 1:1000 dilution of ABIN2868739 was sufficient for detection of Beclin1 on HeLa cell lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

    别名

    Beclin 1

    背景

    Beclin 1 is the mammalian ortholog of the yeast autophagy -related gene Atg6. It regulates autophagy and has an important role in development, tumorigenesis and neurodegeneration (1). Beclin 1 is localized within cytoplasmic structures including the mitochondria, yet overexpression reveals some nuclear staining (2). Researchers have found that schizonphrenia is associated with low levels of Beclin-1 in the hippocampus (3). It may also protect against infection by a neuorvirulent strain of Sindbis virus (4).

    基因ID

    8678

    NCBI登录号

    NP_001300927

    UniProt

    Q14457

    途径

    Autophagy
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