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Ubiquilin 1 抗体

This anti-Ubiquilin 1 antibody is a 兔 多克隆 antibody detecting Ubiquilin 1 in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN2856811
发货至: 中国

Quick Overview for Ubiquilin 1 抗体 (ABIN2856811)

抗原

See all Ubiquilin 1 (UBQLN1) 抗体
Ubiquilin 1 (UBQLN1)

适用

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宿主

  • 49
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克隆类型

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多克隆

标记

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This Ubiquilin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 交叉反应

    产品特性

    Rabbit polyclonal antibody to Ubiquilin-1 (ubiquilin 1)
    Ubiquilin-1 antibody [N1C1]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Ubiquilin 1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Ubiquilin 1 (UBQLN1)

    别名

    ubiquilin 1

    背景

    This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Cytoplasm , Nucleus

    分子量

    63 kDa

    基因ID

    29979

    UniProt

    Q9UMX0
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