SMC1A 抗体 (N-Term)
Quick Overview for SMC1A 抗体 (N-Term) (ABIN2856699)
抗原
See all SMC1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人, 斑马鱼
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产品特性
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Rabbit Polyclonal antibody to SMC1A (structural maintenance of chromosomes 1A)
SMC1A antibody [N1N2], N-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human SMC1A. The exact sequence is proprietary.
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亚型
- IgG
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anti-Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibody
SMC1A 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodySMC1A 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibodySMC1A 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibodySMC1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodySMC1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 8C11 unconjugated Recombinant Antibody
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodySMC1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (AA 366-465) antibodySMC1A 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B9 unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (C-Term) antibodySMC1A 适用: 人 WB, IP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (C-Term) antibodySMC1A 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibodySMC1A 适用: 人 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Molt-4
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
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别名
- structural maintenance of chromosomes 1A
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背景
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Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.
Cellular Localization: Nucleus , Kinetochore -
分子量
- 143 kDa
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基因ID
- 8243
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UniProt
- Q14683
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途径
- Stem Cell Maintenance
抗原
-
