SIGLEC7 抗体
Quick Overview for SIGLEC7 抗体 (ABIN2856478)
抗原
See all SIGLEC7 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to Siglec 7 (sialic acid binding Ig-like lectin 7)
Siglec 7 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Siglec 7. The exact sequence is proprietary.
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亚型
- IgG
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anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 377-467) antibody
SIGLEC7 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 38-121) antibodySIGLEC7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) antibody (PE)SIGLEC7 适用: 人 FACS 宿主: 小鼠 Monoclonal 6-434 PE
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 18-353) antibodySIGLEC7 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 1-467) antibodySIGLEC7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) antibodySIGLEC7 适用: 人 FACS 宿主: 小鼠 Monoclonal 6-434 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 18-353) antibodySIGLEC7 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 1-30), (N-Term) antibodySIGLEC7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2711 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 1-30) antibodySIGLEC7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 407-438) antibodySIGLEC7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: K562 , THP-1 , HL-60 , NCI-H929
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
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别名
- sialic acid binding Ig like lectin 7
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背景
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Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
Cellular Localization: Membrane, Single-pass type I membrane protein -
分子量
- 51 kDa
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基因ID
- 27036
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UniProt
- Q9Y286
抗原
-
