KPNA2 抗体 (C-Term)
(1 reference)Quick Overview for KPNA2 抗体 (C-Term) (ABIN2856324)
抗原
See all KPNA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 小鼠, 大鼠, 猕猴, Chimpanzee
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交叉反应 （详细）
- Mouse (100 %), Rat (100 %), Rhesus Monkey (92 %), Chimpanzee (100 %)
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产品特性
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Rabbit polyclonal antibody to karyopherin alpha 2 (karyopherin alpha 2 (RAG cohort 1, importin alpha 1))
karyopherin alpha 2 antibody [C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human karyopherin alpha 2. The exact sequence is proprietary.
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亚型
- IgG
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anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 1-530) antibody
KPNA2 适用: 人, 小鼠 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1E8B7 unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 157-412) antibodyKPNA2 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 2-285) antibodyKPNA2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (C-Term) antibodyVerified KPNA2 适用: 人, 大鼠 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 1-290) antibodyKPNA2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 157-412) antibodyKPNA2 适用: 人 WB, IF, ICC, FACS 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) antibodyKPNA2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 420-528) antibodyKPNA2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 1-529) antibodyKPNA2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (C-Term) antibody (Biotin)Verified KPNA2 适用: 人 WB, ELISA, IF 宿主: 山羊 Polyclonal Biotin
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: 293T , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.71 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Facioscapulohumeral muscular dystrophy region gene 1 is a dynamic RNA-associated and actin-bundling protein." in: Journal of molecular biology, Vol. 411, Issue 2, pp. 397-416, (2011) (PubMed).
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: "Facioscapulohumeral muscular dystrophy region gene 1 is a dynamic RNA-associated and actin-bundling protein." in: Journal of molecular biology, Vol. 411, Issue 2, pp. 397-416, (2011) (PubMed).
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- KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
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别名
- Karyopherin alpha 2
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背景
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The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination
Cellular Localization: Cytoplasm , Nucleus -
分子量
- 58 kDa
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基因ID
- 3838
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途径
- M Phase, Protein targeting to Nucleus
抗原
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