MAPKAP Kinase 5 抗体
Quick Overview for MAPKAP Kinase 5 抗体 (ABIN2856185)
抗原
See all MAPKAP Kinase 5 (MAPKAPK5) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人
-
产品特性
-
Rabbit Polyclonal antibody to PRAK (mitogen-activated protein kinase-activated protein kinase 5)
PRAK antibody [N1C1] -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human PRAK. The exact sequence is proprietary.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: HepG2
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
-
别名
- mitogen-activated protein kinase-activated protein kinase 5
-
背景
-
The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.
Cellular Localization: Cytoplasm (Probable) , Nucleus -
分子量
- 54 kDa
-
基因ID
- 8550
-
UniProt
- Q8IW41
-
途径
- MAPK Pathway
抗原
-