MBD2 抗体 (Center)
Quick Overview for MBD2 抗体 (Center) (ABIN2856140)
抗原
See all MBD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- 小鼠, 大鼠, 非洲爪蟾
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交叉反应 （详细）
- Mouse (98 %), Rat (98 %), Xenopus laevis (89 %)
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产品特性
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Rabbit polyclonal antibody to MBD2 (methyl-CpG binding domain protein 2)
MBD2 antibody [N2C3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human MBD2. The exact sequence is proprietary.
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亚型
- IgG
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anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (Internal Region) antibody
Verified MBD2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 250-279) antibodyMBD2 适用: 人 WB, IF 宿主: 兔 Polyclonal RB41663 unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (N-Term) antibodyMBD2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 145-411) antibodyMBD2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 10-228) antibodyMBD2 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1812CT625-9-45 unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 202-411) antibodyMBD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) antibodyMBD2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (Middle Region) antibodyMBD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (N-Term) antibodyMBD2 适用: 人, 小鼠, 大鼠, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 361-411) antibodyMBD2 适用: 人, 小鼠, 犬, 豚鼠, Pig WB, IHC, IP, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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说明
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Positive Control: A431 , Jurkat , Raji
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.48 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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别名
- MBD2
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背景
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DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.
Cellular Localization: Nucleus -
分子量
- 43 kDa
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基因ID
- 8932
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途径
- Chromatin Binding
抗原
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