PIK3 gamma 抗体 (C-Term)
Quick Overview for PIK3 gamma 抗体 (C-Term) (ABIN2855878)
抗原
See all PIK3 gamma (PIK3CG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 小鼠, 斑马鱼, Xenopus tropicalis, 猪, 小鸡, 猕猴
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交叉反应 (详细)
- Mouse (100 %), Zebrafish (85 %), Xenopus Tropicalis (92 %), Pig (100 %), Chicken (92 %), Rhesus Monkey (100 %)
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产品特性
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Rabbit Polyclonal antibody to PI3 kinase p110 gamma (phosphoinositide-3-kinase, catalytic, gamma polypeptide)
PI3K gamma antibody [C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PI3K gamma. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: PI 3-kinase p110gamma tansfected 293T cell , Neuro 2A , C8D30 , Raw264.7
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
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别名
- PI3K gamma
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背景
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This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.
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分子量
- 126 kDa
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基因ID
- 5294
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途径
- PI3K-Akt Signaling, RTK signaling, AMPK Signaling, TLR signaling, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
抗原
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