Kallikrein 6 抗体
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北京 101111
Quick Overview for Kallikrein 6 抗体 (ABIN2855841)
抗原
See all Kallikrein 6 (KLK6) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to Kallikrein 6 (kallikrein-related peptidase 6)
Kallikrein 6 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Kallikrein 6. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.88 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Kallikrein 6 (KLK6)
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别名
- kallikrein related peptidase 6
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背景
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Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Cellular Localization: Secreted , Nucleus , nucleolus , Cytoplasm , Mitochondrion , Microsome -
分子量
- 27 kDa
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基因ID
- 5653
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UniProt
- Q92876
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途径
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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