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TIMELESS 抗体 (N-Term)

This anti-TIMELESS antibody is a 兔 多克隆 antibody detecting TIMELESS in WB, IF, IHC (p) 和 ICC. Suitable for 人.
产品编号 ABIN2855809
发货至: 中国

Quick Overview for TIMELESS 抗体 (N-Term) (ABIN2855809)

抗原

See all TIMELESS 抗体
TIMELESS (Timeless Homolog (TIMELESS))

适用

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宿主

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克隆类型

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多克隆

标记

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This TIMELESS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • 抗原表位

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    N-Term

    交叉反应

    小鼠, 大鼠

    交叉反应 (详细)

    Mouse (91 %), Rat (91 %)

    产品特性

    Rabbit Polyclonal antibody to Timeless (timeless homolog (Drosophila))
    Timeless antibody [N1N2], N-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human TIMELESS. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

    说明

    Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Raji

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TIMELESS (Timeless Homolog (TIMELESS))

    别名

    Timeless

    背景

    Required for normal progression of S-phase. Involved in the circadian rhythm autoregulatory loop. Negatively regulates CLOCK-NPAS2/BMAL1-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Promotes TIPIN nuclear localiZation. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.

    Cellular Localization: Nucleus

    分子量

    139 kDa

    基因ID

    8914

    途径

    Protein targeting to Nucleus, Photoperiodism
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