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NOX1 抗体

This anti-NOX1 antibody is a 兔 多克隆 antibody detecting NOX1 in WB, ICC, IHC (p) 和 IF. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2855720
发货至: 中国

Quick Overview for NOX1 抗体 (ABIN2855720)

抗原

See all NOX1 抗体
NOX1 (NADPH Oxidase 1 (NOX1))

适用

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宿主

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克隆类型

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多克隆

标记

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This NOX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to NOX1 (NADPH oxidase 1)
    NOX1 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human NOX1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: JC , BCL-1 , 293T , A431 , HeLa

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.19 mg/mL

    缓冲液

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Liang, Ma, Zhong, Dhar, Liu, Xu, Koyama, Nishio, Karin, Karin, Mccubbin, Zhang, Hu, Yang, Chen, Ganguly, Lan, Karin, Kisseleva, Brenner: "NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice." in: Gastroenterology, Vol. 156, Issue 4, pp. 1156-1172.e6, (2019) (PubMed).

    Sandrini, Ieraci, Amadio, Popoli, Tremoli, Barbieri: "Apocynin Prevents Abnormal Megakaryopoiesis and Platelet Activation Induced by Chronic Stress." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 9258937, (2018) (PubMed).

  • 抗原

    NOX1 (NADPH Oxidase 1 (NOX1))

    别名

    NADPH oxidase 1

    背景

    Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Membrane, Multi-pass membrane protein

    分子量

    65 kDa

    基因ID

    27035

    UniProt

    Q9Y5S8

    途径

    Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport
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