TXNRD1 抗体
Quick Overview for TXNRD1 抗体 (ABIN2855577)
抗原
See all TXNRD1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit polyclonal antibody to TrxR1 (thioredoxin reductase 1)
TrxR1 antibody [N1N3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human TrxR1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Thioredoxin Reductase 1 (TXNRD1) (AA 374-577) antibody
TXNRD1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 451-550) antibodyTXNRD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 208-433) antibodyTXNRD1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 1-497) antibodyTXNRD1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 1-497) antibodyTXNRD1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (C-Term) antibodyVerified TXNRD1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 161-647) antibodyTXNRD1 适用: 人 WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal AT30F1 unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 1-497) antibodyTXNRD1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 271-305) antibodyTXNRD1 适用: 人 WB 宿主: 兔 Polyclonal RB56182 unconjugated
anti-Thioredoxin Reductase 1 (TXNRD1) (AA 516-550) antibodyTXNRD1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB56183 unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
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别名
- thioredoxin reductase 1
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背景
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This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
Cellular Localization: Cytoplasm , Isoform 4: Cytoplasm , Nucleus , Isoform 5: Cytoplasm -
分子量
- 71 kDa
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基因ID
- 7296
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UniProt
- Q16881
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途径
- Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
抗原
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