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TXNRD1 抗体

The 兔 多克隆 anti-TXNRD1 antibody (ABIN2855577) specifically detects TXNRD1 in WB, ICC, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN2855577
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TXNRD1 抗体 (ABIN2855577)

抗原

See all TXNRD1 抗体
TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TXNRD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit polyclonal antibody to TrxR1 (thioredoxin reductase 1)
    TrxR1 antibody [N1N3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human TrxR1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HepG2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

    别名

    thioredoxin reductase 1

    背景

    This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

    Cellular Localization: Cytoplasm , Isoform 4: Cytoplasm , Nucleus , Isoform 5: Cytoplasm

    分子量

    71 kDa

    基因ID

    7296

    UniProt

    Q16881

    途径

    Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
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