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LIG3 抗体

This anti-LIG3 antibody is a 兔 多克隆 antibody detecting LIG3 in WB, IF, ICC 和 IHC (p). Suitable for 人.
产品编号 ABIN2855567
发货至: 中国

Quick Overview for LIG3 抗体 (ABIN2855567)

抗原

See all LIG3 抗体
LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

适用

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宿主

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克隆类型

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多克隆

标记

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This LIG3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to DNA ligase III (ligase III, DNA, ATP-dependent)
    DNA ligase III antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human DNA ligase III. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , HeLa , HepG2

    Validation: KO/KD, Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.81 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

    别名

    DNA ligase 3

    背景

    This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Cellular Localization: Nucleus

    分子量

    113 kDa

    基因ID

    3980

    UniProt

    P49916

    途径

    DNA Damage Repair
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