LIG3 抗体
Quick Overview for LIG3 抗体 (ABIN2855567)
抗原
See all LIG3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit Polyclonal antibody to DNA ligase III (ligase III, DNA, ATP-dependent)
DNA ligase III antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human DNA ligase III. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , A431 , HeLa , HepG2
Validation: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.81 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))
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别名
- DNA ligase 3
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背景
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This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Cellular Localization: Nucleus -
分子量
- 113 kDa
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基因ID
- 3980
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UniProt
- P49916
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途径
- DNA Damage Repair
抗原
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