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TP53BP1 抗体 (N-Term)

The 兔 多克隆 anti-TP53BP1 antibody (ABIN2855433) specifically detects TP53BP1 in WB, IF, ICC, IHC (p) 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN2855433
发货至: 中国
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Quick Overview for TP53BP1 抗体 (N-Term) (ABIN2855433)

抗原

See all TP53BP1 抗体
TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TP53BP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

质量等级

KO Validated
  • 抗原表位

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    N-Term

    交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to 53BP1 (tumor protein p53 binding protein 1)
    53BP1 antibody [N1], N-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human 53BP1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , HeLa , Neuro 2A , C8D30 , NIH-3T3

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

    别名

    tumor protein p53 binding protein 1

    背景

    May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.

    Cellular Localization: Nucleus , Kinetochore

    分子量

    214 kDa

    基因ID

    7158

    UniProt

    Q12888

    途径

    DNA Damage Repair
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