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CDC25A 抗体 (N-Term)

This anti-CDC25A antibody is a 兔 多克隆 antibody detecting CDC25A in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2855354
发货至: 中国

Quick Overview for CDC25A 抗体 (N-Term) (ABIN2855354)

抗原

See all CDC25A 抗体
CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

适用

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宿主

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克隆类型

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多克隆

标记

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This CDC25A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to CDC25A (cell division cycle 25 homolog A (S. pombe))
    CDC25A antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human CDC25A. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: H1299 , MCF-7

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

    别名

    cell division cycle 25A

    背景

    CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    59 kDa

    基因ID

    993

    UniProt

    P30304

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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