ARHGEF18 抗体 (Center)
(3 references)Quick Overview for ARHGEF18 抗体 (Center) (ABIN2855329)
抗原
See all ARHGEF18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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产品特性
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Rabbit Polyclonal antibody to ARHGEF18 (Rho/Rac guanine nucleotide exchange factor (GEF) 18)
ARHGEF18 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human ARHGEF18. The exact sequence is proprietary.
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亚型
- IgG
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anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (AA 159-551) antibody
ARHGEF18 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (AA 1-89) antibodyARHGEF18 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 8H6 unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (C-Term) antibodyVerified ARHGEF18 适用: 人 ELISA, WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (AA 159-551) antibodyARHGEF18 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) antibody (HRP)ARHGEF18 适用: 人, 犬 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) antibody (Biotin)ARHGEF18 适用: 人, 犬 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) antibody (FITC)ARHGEF18 适用: 人, 犬 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.43 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly." in: Cell reports, Vol. 32, Issue 3, pp. 107924, (2020) (PubMed).
: "Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs." in: eLife, Vol. 7, (2018) (PubMed).
: "An apical MRCK-driven morphogenetic pathway controls epithelial polarity." in: Nature cell biology, Vol. 19, Issue 9, pp. 1049-1060, (2017) (PubMed).
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: "Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly." in: Cell reports, Vol. 32, Issue 3, pp. 107924, (2020) (PubMed).
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- ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))
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别名
- ARHGEF18
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背景
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Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.
Cellular Localization: Cytoplasm -
分子量
- 131 kDa
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基因ID
- 23370
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途径
- Neurotrophin Signaling Pathway
抗原
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