CD44 抗体
(3 references)Quick Overview for CD44 抗体 (ABIN2855292)
Key Features
- High quality CD44 Primary Antibody for the detection of CD44.
- Reliable product with high standard validation data
抗原
See all CD44 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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特异性
- IP/MS validation was supported by references (PMID:30377381)
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交叉反应
- 人, 兔, 大鼠
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产品特性
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Rabbit Polyclonal antibody to CD44 (CD44 Molecule (Indian blood group))
CD44 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human CD44. The exact sequence is proprietary.
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亚型
- IgG
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Product Specific Information
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- What can the CD44 Antibody ABIN2855292 be used for?
- This polyclonal CD44 Antibody detects CD44. The CD44 Antibody has been validated for various applications and can be used for the detection of CD44 and derivatives by Western Blotting, Immunofluorescence, Immunohistochemistry (Paraffin-embedded Sections), Immunoprecipitation, Immunohistochemistry (Frozen Sections), Immunocytochemistry, Live Cell Imaging.
- What validation data is available for this CD44 Antibody?
- The Primary Antibody is referenced in 3 publications and is characterized by a proven, very high reliability. It has currently 8 product images that show its performance in a variety of applications. The product is currently available in 100 μL quantity. CD44 Antibody for the detection of CD44 and derivatives.
- What is the function of CD44?
- The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].
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anti-CD44 (CD44) antibody
CD44 适用: 人, 小鼠 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8E2F3 unconjugated
anti-CD44 (CD44) (AA 21-220) antibodyCD44 适用: 人 FACS, WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 6G2D2 unconjugated
anti-CD44 (CD44) antibodyCD44 适用: 人 FACS, WB, IHC, ELISA, IHC (p), IP, Inhibition 宿主: 小鼠 Monoclonal MEM-85 unconjugated
anti-CD44 (CD44) antibodyCD44 适用: 人, 犬, Pig FACS, WB, IHC (p), IP 宿主: 小鼠 Monoclonal MEM-263 unconjugated
anti-CD44 (CD44) (AA 148-247) antibodyCD44 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 36-194) antibodyCD44 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7F4F1 unconjugated
anti-CD44 (CD44) (AA 21-259) antibodyCD44 适用: 人, 小鼠, 大鼠 FACS, WB, IHC, ELISA, IF, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 1-361) antibodyCD44 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-CD44 (CD44) antibodyCD44 适用: 人, Baboon, Green Monkey FACS, WB, IHC, IF, Func, StM 宿主: 小鼠 Monoclonal 156-3C11 unconjugated
anti-CD44 (CD44) (AA 35-300) antibodyCD44 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: MDA-MB-231(24 μg/ml Tunicamycin treatment for 16 hr) , HeLa(12 μg/ml Tunicamycin treatment for 48 hr)
Validation: Comparison, IP/MS, KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Generation and Characterization of Induced Pluripotent Stem Cells and Retinal Organoids From a Leber's Congenital Amaurosis Patient With Novel RPE65 Mutations." in: Frontiers in molecular neuroscience, Vol. 12, pp. 212, (2019) (PubMed).
: "Integrin β3 and CD44 levels determine the effects of the OPN-a splicing variant on lung cancer cell growth." in: Oncotarget, Vol. 7, Issue 34, pp. 55572-55584, (2018) (PubMed).
: "Combination Twist1 and CA15-3 in axillary lymph nodes for breast cancer prognosis." in: Molecular medicine reports, Vol. 15, Issue 3, pp. 1123-1134, (2017) (PubMed).
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: "Generation and Characterization of Induced Pluripotent Stem Cells and Retinal Organoids From a Leber's Congenital Amaurosis Patient With Novel RPE65 Mutations." in: Frontiers in molecular neuroscience, Vol. 12, pp. 212, (2019) (PubMed).
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- CD44
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别名
- CD44 molecule (Indian blood group)
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背景
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The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Cellular Localization: Membrane -
分子量
- 82 kDa
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基因ID
- 960
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UniProt
- P16070
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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