BMI1 抗体 (Center)
Quick Overview for BMI1 抗体 (Center) (ABIN2855259)
抗原
See all BMI1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Center
-
产品特性
-
Rabbit Polyclonal antibody to Bmi1 (BMI1 polycomb ring finger oncogene)
Bmi1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human Bmi1. The exact sequence is proprietary.
-
亚型
- IgG
-
-
-
-
应用备注
- Suggested dilution Reference Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunoprecipitation1:100-1:500* Western blot1:500-1:3000*
-
说明
-
Positive Control: K562 , THP-1
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
-
别名
- Bmi1
-
背景
-
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Cellular Localization: Nucleus , Cytoplasm -
分子量
- 37 kDa
-
基因ID
- 648
-
途径
- Cell Division Cycle, Autophagy
抗原
-