Calnexin 抗体 (Internal Region)
Quick Overview for Calnexin 抗体 (Internal Region) (ABIN2855124)
抗原
See all Calnexin (CANX) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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交叉反应
- 小鸡, 犬, 非洲爪蟾, 斑马鱼, 牛
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交叉反应 (详细)
- Chicken (91 %), Dog (94 %), Xenopus laevis (88 %), Zebrafish (82 %), Bovine (94 %)
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产品特性
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Rabbit Polyclonal antibody to Calnexin (calnexin)
Calnexin antibody [N3C2], Internal -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Calnexin. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:10000*
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说明
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Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , NIH-3T3 , PC-12 , Rat2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.87 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA." in: Nature communications, Vol. 11, Issue 1, pp. 1113, (2020) (PubMed).
: "Biofabrication of Cell-Derived Nanovesicles: A Potential Alternative to Extracellular Vesicles for Regenerative Medicine." in: Cells, Vol. 8, Issue 12, (2020) (PubMed).
: "Rainbow trout (Oncorhynchus mykiss) contain two calnexin genes which encode distinct proteins." in: Developmental and comparative immunology, Vol. 42, Issue 2, pp. 211-9, (2014) (PubMed).
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A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA." in: Nature communications, Vol. 11, Issue 1, pp. 1113, (2020) (PubMed).
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- Calnexin (CANX)
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别名
- Calnexin
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背景
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This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
Cellular Localization: Endoplasmic reticulum membrane , Melanosome -
分子量
- 68 kDa
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基因ID
- 821
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途径
- MAPK Pathway, Thyroid Hormone Synthesis
抗原
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