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BID 抗体

This anti-BID antibody is a 兔 多克隆 antibody detecting BID in WB 和 IP. Suitable for 人.
产品编号 ABIN2855009
发货至: 中国

Quick Overview for BID 抗体 (ABIN2855009)

抗原

See all BID 抗体
BID (BH3 Interacting Domain Death Agonist (BID))

适用

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宿主

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克隆类型

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多克隆

标记

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This BID antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)

质量等级

KO Validated
  • 特异性

    IP/MS validation was supported by references (PMID:30377376)

    交叉反应

    产品特性

    Rabbit polyclonal antibody to Bid (BH3 interacting domain death agonist)
    Bid antibody [N1C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Bid. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:1000-1:10000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A431 , 293T

    Validation: IP/MS, KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.8 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    BID (BH3 Interacting Domain Death Agonist (BID))

    别名

    BH3 interacting domain death agonist

    背景

    This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

    Cellular Localization: Cytoplasm , Mitochondrion membrane , BH3-interacting domain death agonist p15: Mitochondrion membrane , BH3-interacting domain death agonist p13: Mitochondrion membrane , Isoform 1: Cytoplasm , Isoform 3: Cytoplasm , Isoform 2: Mitochondrion membrane

    分子量

    22 kDa

    基因ID

    637

    UniProt

    P55957

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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