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Gelsolin 抗体 (C-Term)

This anti-Gelsolin antibody is a 兔 多克隆 antibody detecting Gelsolin in WB, ICC, IHC (p) 和 IF. Suitable for 人.
产品编号 ABIN2854963
发货至: 中国

Quick Overview for Gelsolin 抗体 (C-Term) (ABIN2854963)

抗原

See all Gelsolin (GSN) 抗体
Gelsolin (GSN)

适用

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宿主

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克隆类型

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多克隆

标记

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This Gelsolin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

质量等级

KO Validated
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    C-Term

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to Gelsolin (gelsolin)
    Gelsolin antibody [C2C3], C-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human Gelsolin. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: H1299 , HeLa , human plasma , rat plasma , mouse plasma

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.27 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Gelsolin (GSN)

    别名

    gelsolin

    背景

    The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

    Cellular Localization: Isoform 2: Cytoplasm , cytoskeleton , Isoform 1: Secreted

    分子量

    86 kDa

    基因ID

    2934

    UniProt

    P06396

    途径

    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
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