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CD73 抗体

NT5E 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854948
发货至: 中国
  • 抗原 See all CD73 (NT5E) 抗体
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    适用
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    克隆类型
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    多克隆
    标记
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    This CD73 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    产品特性
    Rabbit polyclonal antibody to CD73 (5'-nucleotidase, ecto (CD73))
    CD73 antibody [N3C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human CD73. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product NT5E Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: H1299

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.97 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    别名
    5'-nucleotidase ecto (NT5E 产品)
    别名
    CALJA antibody, CD73 antibody, E5NT antibody, NT antibody, NT5 antibody, NTE antibody, eN antibody, eNT antibody, zgc:63784 antibody, NT5E antibody, MGC114869 antibody, PSPTO2277 antibody, 2210401F01Rik antibody, AI447961 antibody, Nt5 antibody, 5'-nucleotidase ecto antibody, 5'-nucleotidase, ecto (CD73) antibody, 5'-nucleotidase antibody, 5' nucleotidase, ecto antibody, NT5E antibody, nt5e antibody, nt5e.S antibody, PSPTO_2277 antibody, CBU_1233 antibody, MCA1322 antibody, Nt5e antibody
    背景
    Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase, EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.[supplied by OMIM]

    Cellular Localization: Cell membrane , GPI-anchor
    分子量
    63 kDa
    基因ID
    4907
    UniProt
    P21589
    途径
    Synaptic Membrane, Ribonucleoside Biosynthetic Process
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