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SOCS1 抗体 (C-Term)

This anti-SOCS1 antibody is a 兔 多克隆 antibody detecting SOCS1 in WB, ICC, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN2854825
发货至: 中国

Quick Overview for SOCS1 抗体 (C-Term) (ABIN2854825)

抗原

See all SOCS1 抗体
SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

适用

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宿主

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克隆类型

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多克隆

标记

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This SOCS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to SOCS1 (suppressor of cytokine signaling 1)
    SOCS1 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SOCS1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Mouse brain , HepG2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

    别名

    suppressor of cytokine signaling 1

    背景

    This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

    分子量

    24 kDa

    基因ID

    8651

    UniProt

    O15524

    途径

    JAK/STAT Signaling, Interferon-gamma Pathway, TLR signaling, Response to Growth Hormone Stimulus
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