Periostin 抗体 (C-Term)
Quick Overview for Periostin 抗体 (C-Term) (ABIN2854805)
抗原
See all Periostin (POSTN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit Polyclonal antibody to Periostin (periostin, osteoblast specific factor)
Periostin antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human Periostin. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: H1299
Validation: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.29 mg/mL
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缓冲液
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7), 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization." in: Nature communications, Vol. 11, Issue 1, pp. 4254, (2020) (PubMed).
: "Periostin blockade overcomes chemoresistance via restricting the expansion of mesenchymal tumor subpopulations in breast cancer." in: Scientific reports, Vol. 8, Issue 1, pp. 4013, (2019) (PubMed).
: "SPOCK1 Is a Novel Transforming Growth Factor-β-Induced Myoepithelial Marker That Enhances Invasion and Correlates with Poor Prognosis in Breast Cancer." in: PLoS ONE, Vol. 11, Issue 9, pp. e0162933, (2017) (PubMed).
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Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization." in: Nature communications, Vol. 11, Issue 1, pp. 4254, (2020) (PubMed).
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- Periostin (POSTN)
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别名
- periostin
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背景
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Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.
Cellular Localization: Secreted , extracellular space , extracellular matrix -
分子量
- 93 kDa
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基因ID
- 10631
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UniProt
- Q15063
抗原
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