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Periostin 抗体 (C-Term)

There are 3+ publications for this product available. The 兔 多克隆 anti-Periostin antibody is suitable to detect Periostin in samples from 人. It has been validated for WB, ICC, IF, IHC (p) 和 IHC (fro).
产品编号 ABIN2854805
发货至: 中国
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Quick Overview for Periostin 抗体 (C-Term) (ABIN2854805)

抗原

See all Periostin (POSTN) 抗体
Periostin (POSTN)

适用

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宿主

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克隆类型

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多克隆

标记

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This Periostin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    C-Term

    交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to Periostin (periostin, osteoblast specific factor)
    Periostin antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human Periostin. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: H1299

    Validation: KO/KD, Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.29 mg/mL

    缓冲液

    1XPBS, 1 % BSA, 20 % Glycerol ( pH 7), 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Lee, Yeh, Lee, Shih, Chen, Hung, You, Wu, Shentu, Huang, Lin, Wu, Lin, Lu, Tsao, Lin, Lo, Tseng, Wu, Chen, Wu, Lin, Sperling, Guzy, Fang, Yang: "Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization." in: Nature communications, Vol. 11, Issue 1, pp. 4254, (2020) (PubMed).

    Nakazawa, Taniyama, Sanada, Morishita, Nakamori, Morimoto, Yeung, Yang: "Periostin blockade overcomes chemoresistance via restricting the expansion of mesenchymal tumor subpopulations in breast cancer." in: Scientific reports, Vol. 8, Issue 1, pp. 4013, (2019) (PubMed).

    Fan, Jeng, Lu, Lien: "SPOCK1 Is a Novel Transforming Growth Factor-β-Induced Myoepithelial Marker That Enhances Invasion and Correlates with Poor Prognosis in Breast Cancer." in: PLoS ONE, Vol. 11, Issue 9, pp. e0162933, (2017) (PubMed).

  • 抗原

    Periostin (POSTN)

    别名

    periostin

    背景

    Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.

    Cellular Localization: Secreted , extracellular space , extracellular matrix

    分子量

    93 kDa

    基因ID

    10631

    UniProt

    Q15063
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