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Retinoblastoma 1 抗体 (C-Term)

This anti-Retinoblastoma 1 antibody is a 兔 多克隆 antibody detecting Retinoblastoma 1 in WB, IF, IP, IHC (p) 和 ICC. Suitable for 人.
产品编号 ABIN2854790
发货至: 中国

Quick Overview for Retinoblastoma 1 抗体 (C-Term) (ABIN2854790)

抗原

See all Retinoblastoma 1 (RB1) 抗体
Retinoblastoma 1 (RB1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Retinoblastoma 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • 抗原表位

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    C-Term

    交叉反应

    猕猴

    交叉反应 (详细)

    Rhesus Monkey (100 %)

    产品特性

    Rabbit Polyclonal antibody to Rb (retinoblastoma 1)
    Rb antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human Rb. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

    说明

    Positive Control: A431 , *CL1-0 , *CL1-5 ,

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Retinoblastoma 1 (RB1)

    别名

    Rb

    背景

    The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

    Cellular Localization: Nucleus

    分子量

    106 kDa

    基因ID

    5925

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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