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CCR3 抗体 (C-Term)

This anti-CCR3 antibody is a 兔 多克隆 antibody detecting CCR3 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2854719
发货至: 中国

Quick Overview for CCR3 抗体 (C-Term) (ABIN2854719)

抗原

See all CCR3 抗体
CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

适用

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宿主

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克隆类型

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多克隆

标记

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This CCR3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    交叉反应

    产品特性

    Rabbit Polyclonal antibody to CCR3 (chemokine (C-C motif) receptor 3)
    CCR3 antibody [C2C3], C-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CCR3. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: K562

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

    别名

    C-C motif chemokine receptor 3

    背景

    The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants encoding the same protein have been described.

    Cellular Localization: Cell membrane

    分子量

    41 kDa

    基因ID

    1232

    UniProt

    P51677
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