CISH 抗体 (C-Term)
Quick Overview for CISH 抗体 (C-Term) (ABIN2854656)
抗原
See all CISH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人, 大鼠
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产品特性
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Rabbit Polyclonal antibody to CIS (cytokine inducible SH2-containing protein)
CIS antibody [C2C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CIS. The exact sequence is proprietary.
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亚型
- IgG
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anti-Cytokine Inducible SH2-Containing Protein (CISH) (AA 1-258) antibody
CISH 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Inducible SH2-Containing Protein (CISH) (AA 1-258) antibodyCISH 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cytokine Inducible SH2-Containing Protein (CISH) (AA 1-258) antibodyCISH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Inducible SH2-Containing Protein (CISH) (AA 79-256) antibodyCISH 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Inducible SH2-Containing Protein (CISH) (AA 1-257) antibodyCISH 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Inducible SH2-Containing Protein (CISH) (AA 17-130) antibodyCISH 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Inducible SH2-Containing Protein (CISH) (AA 241-258), (C-Term) antibodyCISH 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Inducible SH2-Containing Protein (CISH) (AA 241-258) antibodyCISH 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Inducible SH2-Containing Protein (CISH) (AA 78-127) antibodyCISH 适用: 人, 小鼠, 大鼠, Pig, Cow, 马, 兔, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Inducible SH2-Containing Protein (CISH) antibodyCISH 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HeLa , PC-12 , Rat2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CISH (Cytokine Inducible SH2-Containing Protein (CISH))
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别名
- cytokine inducible SH2 containing protein
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背景
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The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 29 kDa
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基因ID
- 1154
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UniProt
- Q9NSE2
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途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
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