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NOTCH3 抗体 (C-Term)

This anti-NOTCH3 antibody is a 兔 多克隆 antibody detecting NOTCH3 in WB. Suitable for 人.
产品编号 ABIN2854480
发货至: 中国

Quick Overview for NOTCH3 抗体 (C-Term) (ABIN2854480)

抗原

See all NOTCH3 抗体
NOTCH3 (Notch 3 (NOTCH3))

适用

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宿主

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克隆类型

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多克隆

标记

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This NOTCH3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    交叉反应

    小鼠, 大鼠

    交叉反应 (详细)

    Mouse (100 %), Rat (100 %)

    产品特性

    Rabbit polyclonal antibody to Notch 3 (Notch homolog 3 (Drosophila))
    Notch 3 antibody [C3], C-term

    纯化方法

    Affinity purified by Protein A.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Notch 3. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

    说明

    Positive Control: HeLa

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    5.26 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    NOTCH3 (Notch 3 (NOTCH3))

    别名

    Notch 3

    背景

    This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

    Cellular Localization: Cell membrane, Single-pass type I membrane protein , Notch 3 intracellular domain: Nucleus

    分子量

    244 kDa

    基因ID

    4854

    途径

    Notch Signaling
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