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MUTYH 抗体 (Center)

This anti-MUTYH antibody is a 兔 多克隆 antibody detecting MUTYH in WB. Suitable for 人 和 小鼠.
产品编号 ABIN2854424
发货至: 中国

Quick Overview for MUTYH 抗体 (Center) (ABIN2854424)

抗原

See all MUTYH 抗体
MUTYH (MutY Homolog (E. Coli) (MUTYH))

适用

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人, 小鼠

宿主

  • 48
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克隆类型

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多克隆

标记

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This MUTYH antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Center

    产品特性

    Rabbit polyclonal antibody to MYH (mutY homolog (E. coli))
    MUTYH antibody [N3C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human MUTYH. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

    说明

    Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , NIH-3T3

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.39 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    MUTYH (MutY Homolog (E. Coli) (MUTYH))

    别名

    MUTYH

    背景

    This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Nucleus

    分子量

    60 kDa

    基因ID

    4595

    途径

    DNA Damage Repair
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