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IL12RB2 抗体

IL12RB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854423
发货至: 中国
  • 抗原 See all IL12RB2 抗体
    IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
    适用
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    宿主
    • 59
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    克隆类型
    • 62
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    多克隆
    标记
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    This IL12RB2 antibody is un-conjugated
    应用范围
    • 58
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    Western Blotting (WB)
    交叉反应
    产品特性
    Rabbit polyclonal antibody to IL-12 Receptor beta2 (interleukin 12 receptor, beta 2)
    IL-12 Receptor beta2 antibody [N3C2], Internal
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human IL12 Receptor beta2. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product IL12RB2 Primary Antibody
  • 应用备注
    WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: A431 , HepG2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
    别名
    interleukin 12 receptor subunit beta 2 (IL12RB2 产品)
    别名
    IL12RB2 antibody, A930027I18Rik antibody, IL-12RB2 antibody, Ifnm antibody, interleukin 12 receptor subunit beta 2 antibody, interleukin 12 receptor, beta 2 antibody, IL12RB2 antibody, Il12rb2 antibody
    背景
    The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    分子量
    97 kDa
    基因ID
    3595
    UniProt
    Q99665
    途径
    JAK/STAT Signaling
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